Different Modes of Transport for 3H-Thymidine, 3H-FLT, and 3H-FMAU in Proliferating and Nonproliferating Human Tumor Cells
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منابع مشابه
Incorporation of [3H]thymidine in mouse spleen.
Mice were given 4 injections of [H]thymidine at 2-hourly intervals and killed at times varying from 1 h to 12 days after the last injection. Autoradiographs of spleen, oesophagus and heart were prepared by the stripping-film technique and exposed for 21, 189 and 367 days. Groups of lymphoid cells surrounding trabeculae were heavily labelled, the decline in grain count suggesting division of the...
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The satellite cell (6) is a mononucleated cell that is wedged between the multinucleated muscle syncytium and the basal membrane of the myofiber. These cells are described in skeletal muscle of amphibians (6, 7) and mammals (3, 12-14). From data in the literature it is clear that satellite cells are most abundant during embryonic life, though it is not obvious that they participate in the norma...
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Epithelial cell proliferation was studied in the normal colonic mucosa of 5-week-old Sprague-Dawley rats, comparing [3H]thymidine incorporation (group 1) with two newer proliferation markers, bromodeoxyuridine (group 2) and proliferating cell nuclear antigen (group 3). Microautoradiography (group 1) or immunoperoxidase assays (groups 2 and 3) were carried out. Cells were counted for positive re...
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Microautoradiography was employed to show that association of drugs from the serum directly with forming hair pigment is a primary pathway of deposition into the hair. After systemic administration of [3H]flunitrazepam, [3H]nicotine, and [3H]cocaine, association of all three drugs with melanin in the forming hair was observed within minutes of dosage. Sebum was determined to be an insignificant...
متن کاملMalnutrition: Incorporation of Thymidine-3h into Nuclear and Mitochondrial Dna
Protein-calorie malnutrition or fasting leads to a readily detectable decrease in the rate of body growth and cellular proliferation, particularly in young animals (32, 33) . In contrast, disorders in cell and organ function have generally been more difficult to demonstrate, perhaps partly due to limitations in methodology (8, 16, 22) . Mitochondria are the primary energy source for the work of...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2010
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.110.076794